Type R Ketamine is a specific enantiomer or “mirror image” of ketamine, often associated with fewer dissociative effects and a gentler experience compared to the traditional racemic ketamine. Like other forms of ketamine, it acts as an NMDA receptor antagonist, commonly used in therapeutic settings to manage treatment-resistant depression, PTSD, and certain anxiety disorders. The unique properties of Type R Ketamine make it especially valuable in therapies seeking fewer dissociative side effects while still benefiting from ketamine’s antidepressant and anxiolytic effects.

1. Dose

• Therapeutic Dosage: The dose of Type R Ketamine is typically lower than racemic ketamine and adjusted based on patient needs, often administered through IV, IM, or oral routes in a clinical setting.
• Dose Adjustment: Dosages are tailored to minimize dissociation, allowing patients to remain aware and engaged during therapy sessions.

2. Preparation

• Hydration and Nutrition: It’s beneficial to hydrate and have a balanced meal prior to therapy.
• Calm Environment: A quiet, comfortable setting with a therapist present is ideal, as it promotes relaxation and minimizes anxiety.

3. During Use

• Professional Supervision: Type R Ketamine is usually administered in low doses with medical oversight to monitor for any adverse effects.
• Mindfulness: No additional substances (such as alcohol) should be combined with ketamine, as interactions can amplify side effects and increase risks.

4. Post-Use Care

• • Rest and Recovery: After the session, patients may experience mild fatigue or emotional sensitivity, so adequate rest and nourishment are recommended.
  • Therapeutic Integration: Follow-up therapy sessions help patients process and integrate their experiences, maximizing therapeutic outcomes.

The effects of Type R Ketamine can last between 1 to 2 hours, shorter and gentler than racemic ketamine due to its unique properties. Here’s a breakdown:

1. Onset (5-15 minutes): Effects begin within minutes, with patients often experiencing a calm, grounded state and some mild detachment from stressors.
2. Peak Effects (30-60 minutes): This period typically involves heightened relaxation and a sense of peace, with fewer dissociative experiences than traditional ketamine.
3. Comedown (30-60 minutes): Effects gradually fade, and patients return to a baseline state, often with a clearer perspective and mild relaxation.
4. Aftereffects (up to 24 hours): Some individuals report feeling emotionally lighter or less burdened for up to a day, though fatigue may persist.